ETHYL 2-FLUOROPHENYL KETONE
2'-fluoropropiophenone
CAS: 446-22-0
Molecular Formula: C9H9FO
ETHYL 2-FLUOROPHENYL KETONE - Names and Identifiers
| Name | 2'-fluoropropiophenone |
| Synonyms | 2-FLUOROPROPIOPHENONE o-Fluoropropiophenone 2-Fluoropropiophendne 2-Fluoropropiophenone 2'-fluoropropiophenone 2'-FLUOROPROPIOPHENONE ETHYL 2-FLUOROPHENYL KETONE 2'-fluoro-1-phenylpropan-1-one 1-(2-FLUOROPHENYL)PROPAN-1-ONE 1-(2'-fluorophenyl)propan-1-one |
| CAS | 446-22-0 |
| EINECS | 244-220-7 |
| InChI | InChI=1/C9H9FO/c1-2-9(11)7-5-3-4-6-8(7)10/h3-6H,2H2,1H3 |
ETHYL 2-FLUOROPHENYL KETONE - Physico-chemical Properties
| Molecular Formula | C9H9FO |
| Molar Mass | 152.17 |
| Density | 1.102g/mLat 25°C(lit.) |
| Boling Point | 95-99°C19mm Hg(lit.) |
| Flash Point | 175°F |
| Water Solubility | Soluble in chloroform, methanol. Not miscible in water. |
| Solubility | Chloroform, Methanol |
| Vapor Presure | 0.268mmHg at 25°C |
| Appearance | Oil |
| Specific Gravity | 1.102 |
| Color | Pale Yellow |
| BRN | 3235723 |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | n20/D 1.5043(lit.) |
ETHYL 2-FLUOROPHENYL KETONE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29147000 |
| Hazard Class | IRRITANT |
ETHYL 2-FLUOROPHENYL KETONE - Introduction
2 '-fluoropropiophenone(2'-fluoropropiophenone) is an organic compound with the chemical formula C9H9FO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- 2 '-fluoropropiophenone is a colorless liquid with a special fragrance.
-Its molecular weight is 152.17g/mol and its density is about 1.50g/cm3.
-Soluble in organic solvents such as ethanol, acetone and dimethylformamide at room temperature.
Use:
- 2 '-fluoropropiophenone is an important organic synthesis intermediate, often used in the synthesis of other organic compounds.
-It can be used to prepare chemical products such as drugs, pesticides, dyes and coatings.
Preparation Method:
- 2 '-fluoropropiophenone can generally be synthesized by a cycloaddition reaction of an acid fluoride with styrene. The specific steps include reacting acyl fluoride with styrene in the presence of a catalyst to obtain o-fluoroacetophenone, followed by a series of reaction steps, such as carbonyl reduction and acid catalytic cleavage, to obtain 2 '-fluoropropiophenone.
Safety Information:
- 2 '-fluoropropiophenone need to pay attention to safety during operation and storage, and correct laboratory operating procedures should be followed.
-It may be irritating to the eyes, skin, respiratory system and digestive system, so direct contact should be avoided.
-Avoid inhaling its vapors during use and maintain a well-ventilated laboratory environment.
-If skin contact occurs, immediately rinse the affected area with plenty of water and seek medical help.
-Observe local regulations when handling and disposing of this compound.
Nature:
- 2 '-fluoropropiophenone is a colorless liquid with a special fragrance.
-Its molecular weight is 152.17g/mol and its density is about 1.50g/cm3.
-Soluble in organic solvents such as ethanol, acetone and dimethylformamide at room temperature.
Use:
- 2 '-fluoropropiophenone is an important organic synthesis intermediate, often used in the synthesis of other organic compounds.
-It can be used to prepare chemical products such as drugs, pesticides, dyes and coatings.
Preparation Method:
- 2 '-fluoropropiophenone can generally be synthesized by a cycloaddition reaction of an acid fluoride with styrene. The specific steps include reacting acyl fluoride with styrene in the presence of a catalyst to obtain o-fluoroacetophenone, followed by a series of reaction steps, such as carbonyl reduction and acid catalytic cleavage, to obtain 2 '-fluoropropiophenone.
Safety Information:
- 2 '-fluoropropiophenone need to pay attention to safety during operation and storage, and correct laboratory operating procedures should be followed.
-It may be irritating to the eyes, skin, respiratory system and digestive system, so direct contact should be avoided.
-Avoid inhaling its vapors during use and maintain a well-ventilated laboratory environment.
-If skin contact occurs, immediately rinse the affected area with plenty of water and seek medical help.
-Observe local regulations when handling and disposing of this compound.
Last Update：2024-04-09 20:49:11
